Ramping is a way to
allow the body to get used to a dose, which typically takes two
weeks. The goal is to reach 30 - 40 milligrams per day in four
doses, spread four to five hours apart. I have been reluctant to
give direct recommendations of dosing since you should work with
your doctor. However, I will suggest the following general ramp-up
schedule:
5mg per day – in the morning
- for 2 days
5mg twice daily (breakfast and late afternoon)
for 3 days
5 mg 3 times a day (every 5-6 hours while
awake) for 4 days
= 15 mg/day
5 mg 4 times a day (every 4-5 hours while awake)
for 5 days = 20
mg/day
10 mg (2 of the 5mg capsules) 3 times a day (every 5-6 hours while
awake)
for 6 days
= 30 mg/day
IF TOLERATED, 10 mg 4 times a day; every 4-5 hrs while awake) = 40
mg/day
Such an
approach will get you to the 40mg dose in about two weeks. The
approach assumes that you do not have any side effects such as
tingling, nervousness, insomnia or dizziness at any stage along the
way. If there are side effects, wait until they subside before going
up to the next step. It is probably a good idea for doctors
prescribing 4-AP to initially order 5-milligram capsules for the
ramping-up phase.
It is a good idea to follow a plan and to make every effort to not
try to speed up this process. Some have tried and found themselves
with severe difficulties. Use the form on the back of this note to
record your progress.
OR
Week 1 Take 5mg at 7am
every day
Week 2 Take 5mg at 7am and
3pm every day
Week 3 Take 5mg at 7am,
3pm, and 7pm every day
Week 4 Take 10mg at 7am and
7pm every day
And continue at this level unless advised by physician
(Complements of Dr. Steven G. Ayre).
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