Please refer to
your own saliva test values when reading these pages.
The interplay of hormones is a very complex "dance"
and it is not always easy. Many symptoms and chronic
conditions can be associated with hormone imbalance
and it is usually best to adjust hormone levels by
using bio-identical hormone supplements. The common
commercial HRT products are synthetic or produced from
non-human animal sources. there are great numbers of
side effects associated with those prescription HRT
drugs.
To establish a
good balance between hormones you need to be working
closely with a dedicated doctor and a compounding
pharmacist.
ESTROGEN: Low Normal
We
have found that this sometimes can happen when a
person has used birth control pills or one of the
synthetic types of HRT (Premarin, PremPro, etc.).
When
these estrogen-like products are used there can be a
long term negative effect on the ovaries. In basic
terms, the ovaries get the message from the HRT
drugs that they don't need to make as much estrogen
as they had been making. Over time, this lowered
amount becomes the norm and the ovaries just don't
seem to get started again.
When this happens it is important to consider using
a natural, or bio-identical, estrogen replacement.
ESTROGEN: Low Normal
We
have found that this sometimes can happen when a
person has used birth control pills or one of the
synthetic types of HRT (Premarin, PremPro, etc.).
When
these estrogen-like products are used there can be a
long term negative effect on the ovaries. I basic
terms, the ovaries get the message from the HRT
drugs that they don't need to make as much estrogen
as they had been making. Over time, this lowered
amount becomes the norm and the ovaries just don't
seem to get started again.
When
this happens it is important to consider using a
natural, or bio-identical, estrogen replacement.
However, instead of beginning with an estrogen
supplement, it might be better to consider using
DHEA in a low dose. DHEA is often referred to as a
"pro hormone", meaning that it is the precursor for
the production of other hormones. In women, DHEA can
convert to either estrogen or testosterone -
depending on a woman's need at the time.
DHEA
is available without a prescription. We have found
that a good dose of DHEA is 5mg - taken daily
usually at bedtime. Almost all of the
over-the-counter forms of DHEA are significantly
stronger than this. We've located a 5mg dose that
seems to have been very helpful for many women. It
can be swallowed or allowed to dissolve under the
tongue.
DHEA
is commonly taken at bedtime. Some women produce a
surge in estrogen a few hours after taking the dose
and - estrogen being a stimulant - the woman awakens
early in the morning and finds it difficult to get
back to sleep. For those women we recommend taking
the DHEA during the day. The goal is to generate
sufficient estrogen without overdoing it.
We
recommend giving the DHEA a good trial - 6 to 8
weeks. If there is no improvement it may be time to
consider a full estrogen supplement - using NATURAL,
bio-identical hormones, of course.
ESTROGEN: Normal
If
your symptoms are consistent with low estrogen you
may want to consider using a low dose of DHEA every
day.
DHEA
is a precursor to the hormones in your body. Women
are able to convert DHEA to the appropriate hormones
- when needed. DHEA can be converted to either
estrogen or testosterone. It is important to not
take too much.
The
commercially available DHEA supplements are often
25mg or 50mg. That dose may be alright for a man,
but women usually do best when they use 5 to 10 mg
per day.
ESTROGEN: High Normal
If you
are using any form of estrogen supplement you might
want to consider reducing the dose - or stopping
altogether. If the hormone has been prescribed by
your doctor do not make changes without consulting
him or her.
If
your symptoms are consistent with this elevated
level of estrogen you will want to consider ways to
reduce these levels - particularly if you are
experiencing discomfort.
If you
are not using any form of hormone supplement you can
still reduce the amount of estrogen by a combination
of diet, exercise, and possible, some supplements.
It is
important to make sure that whatever level of
estrogen you have, you balance it with sufficient
progesterone. See the progesterone section and
notice that if your progesterone to estrogen ratio
is under 200 you may want to consider adding
progesterone. Women report they feel best when their
ratio is around 500. Ratios below 200 indicate a
deficiency. Ratios above 1000 are considered
acceptable IF you are using a transdermal
progesterone cream. If your levels are in the
thousands - and you are not using a supplement - you
may want to consider re-testing because your sample
may have been contaminated.
A
dietary approach to lowering estrogen would be to
consume more brascia vegetables - things like
Brussels sprouts, cabbage, cauliflower, etc. These
vegetables contain a chemical that is know to reduce
excess estrogen. You would also want to avoid
sugars, processed carbohydrates, artificial
sweeteners, caffeine, and alcohol.
Modest
exercise is important in maintaining hormone
balance. We recommend a brisk walk of 30 minutes, 3
to 5 times a week.
PROGESTERONE: Below Normal
Progesterone is a key hormone and it must be present
in sufficient quantity to balance efficiently with
estrogen. Progesterone is produced by the corpus
luteum monthly after ovulation. If a pregnancy
occurs, the developing baby takes over the task of
producing this hormone - and it does so in large
quantities.
When
progesterone levels fall rapidly - around the 26th
day of a cycle - your period starts.
Progesterone impacts physical, mental and emotional
health. When it is too low a person could suffer in
one or more of those areas. Some of the symptoms
often associated with low progesterone are anxiety,
anger, nervousness, various pains, and mental
"fogginess".
You
may want to use a progesterone supplement to bring
your levels up.
This
may be accomplished by using an over-the-counter
cream or a prescription product. The
non-prescription product is identical in content to
the one that your doctor may order. The only
difference is the strength.
Our
recommendation for progesterone supplements is the
transdermal cream. They offer dosing flexibility and
they are well absorbed - and there are almost no
difficulties from applying the cream.
Pre-menopausal women who are still having cycles may
want to use the progesterone once daily during the
last half of their cycle - say from days 13 through
25.
If you
are not having periods you should still consider
dosing progesterone according to a cycle - somewhat
copying your normal menstrual cycle. As above, we
recommend a lower dose for the first half of the
month, increasing for another couple of weeks, and
then stopping altogether for a few days. It is
important to give your body the time to allow the
progesterone levels to fall. Constant exposure to
progesterone can make cells unresponsive to
progesterone - and that's like not having enough.
Women who are not having periods can follow a
calendar for their cycle.
PROGESTERONE: Low Normal
Progesterone is a key hormone and it must be present
in sufficient quantity to balance efficiently with
estrogen. Progesterone is produced by the corpus
luteum monthly after ovulation. If a pregnancy
occurs, the developing baby takes over the task of
producing this hormone - and it does so in large
quantities.
When
progesterone levels fall rapidly - around the 26th
day of a cycle - the period starts.
Progesterone impacts physical, mental and emotional
health. When it is too low a person could suffer in
one or more of those areas. Some of the symptoms
often associated with low progesterone are anxiety,
anger, nervousness, various pains, and mental
"fogginess".
It is
important to use a progesterone supplement to bring
your levels up. This may be accomplished by using an
over-the-counter cream or a prescription product.
The non-prescription product is identical in content
to the one that your doctor may order. The only
difference is the strength.
Our
recommendation for progesterone supplements is the
transdermal cream. They offer dosing flexibility and
they are well absorbed - and there are almost no
difficulties from applying the cream.
Pre-menopausal women who are still having cycles may
want to use the progesterone once daily during the
last half of their cycle - say from days 13 through
25.
If you
are not having periods you should still consider
dosing progesterone according to a cycle - somewhat
copying your normal menstrual cycle. As above, we
recommend a lower dose for the first half of the
month, increasing for another couple of weeks, and
then stopping altogether. It is important to give
your body the time to allow the progesterone levels
to fall. Constant exposure to progesterone can make
cells unresponsive to progesterone - and that's like
not having enough. Women who are not having periods
can follow a calendar for their cycle.
PROGESTERONE: Normal
Progesterone is a key hormone and it must be present
in sufficient quantity to balance efficiently with
estrogen. Progesterone is produced by the corpus
luteum monthly after ovulation. If a pregnancy
occurs, the developing baby takes over the task of
producing this hormone - and it does so in large
quantities.
When
progesterone levels fall rapidly - around the 26th
day of a cycle - the period starts. While your level
is in the normal range it may still be responsible
for the symptoms you describe. The absolute level is
less important that the ratio between progesterone
and your estrogen.
When that ration is around 500, most women report
that they feel the best. Levels below 200 usually
indicate an imbalance that is called "Estrogen
Dominance."
PROGESTERONE/ESTROGEN Ratio
The
ratio between progesterone and estradiol is
important. The normal is above 200, yet most women
report they feel best when the ratio is closer to
500. If your ratio is below normal - by a
significant amount. This suggests that you may be
experiencing symptoms that Dr. John Lee called
"estrogen dominance."
Your
estrogen levels may be in the normal range, but if
your progesterone is too low you can experience all
of the symptoms associated with too much estrogen -
that's "estrogen dominance."
PROGESTERONE/ESTROGEN Ratio: High
If
your progesterone to estrogen ratio is a little high
is probably nothing to worry about - unless you are
experiencing symptoms that you don't want. When a
woman uses transdermal progesterone the saliva
values can be 200 or 3000 - or more. That elevates
the ratio and is expected when using a progesterone
supplement.
Some
practitioners get alarmed when they see high
numbers, but the shouldn't. It is expected that
transdermal progesterone will elevate both the
progesterone level and the ratio. Once you begin to
use the cream the symptoms control is far more
important than the actual values.
If you
are feeling a little sluggish, you might want to cut
back just a little on the cream. Our usual
suggestion is 20mg daily on days 1 through 12, twice
daily on days 13 through 25 then stopping.
If
you're using one of our pumpers you can reduce the
dose by just not pressing down all the way on the
pump unit. A "half pump" delivers about 10mg.
It
would be nice if this was all a precise science -
you know, "exactly 16mg on this day and 27mg on
that." But, the fact remains that people are
different - and circumstances change form day to
day. A dose schedule that was fine during one season
may be too much or too little during another. Stress
increases demand for progesterone (and other
hormones), so stressful times may demand a larger
dose. Vacations may reduce the need.
TESTOSTERONE: Low
Testosterone is important for libido (sexual
interest) muscle and skin tone. Too little can
result in thinning skin, loss of hair, dryness and
loss of libido. Too much testosterone is associated
with coarse hair, oily skin, and a deepened voice.
Clearly, a low testosterone level can be responsible
for some of the symptoms you are concerned about.
Testosterone levels can be impacted by progesterone.
There is what we refer to as a "hormone cascade".
This is depiction of how one hormone generates
others - in a sort of cascading effect. For example,
the chief hormone - cholesterol - reacts to form
pregnenolone - and that becomes progesterone. From
this small group can come all of the other hormones
- estrogens, DHEA, testosterone, insulin, cortisol,
thyroid, and so on.
Many
people find that when they get their progesterone
levels up and their progesterone to estrogen ration
closer to 500, their testosterone levels also rise -
because testosterone is farther "down the path" in
the hormone cascade.
Our
usual recommendation is to start using a
progesterone supplement to see if testosterone
levels rise naturally. This does not require a
prescription because progesterone can be purchased
over the counter (without a prescription).
If
this isn't sufficient to bring testosterone levels
up, you may need to supplement of testosterone -
usually as a transdermal cream. This requires a
prescription from a doctor. It consists of a cream
that contains testosterone in a low dose. Women
begin by using 0.25mg daily. This dose is increased
every 7 to 10 days until the proper results are
achieved.
Sometimes using testosterone can stimulate the
normal production and the woman can stop using the
testosterone cream. Other women find they need a
continuous supplement - so they get their
testosterone refilled regularly.
TESTOSTERONE: Low Normal
Testosterone is important for libido (sexual
interest) muscle and skin tone. Too little can
result in thinning skin, loss of hair, dryness and
loss of libido. Too much testosterone is associated
with coarse hair, oily skin, and a deepened voice.
Clearly, a low testosterone level can be responsible
for some uncomfortable symptoms. Keep in mind, that
this level may be "normal" for you. Before moving to
a testosterone replacement it may be a good plan to
use other supplements that have been shown to
improve balance and raise testosterone levels.
TESTOSTERONE: High
Testosterone is important for libido (sexual
interest) muscle and skin tone. Too little can
result in thinning skin, loss of hair, dryness and
loss of libido. Too much testosterone is associated
with coarse hair, oily skin, and a deepened voice.
Elevated testosterone is a problem we don't have an
answer for.
Please evaluate
your situation and talk to your doctor about your
needs.
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