Dr. Al Sears recommends 200mg to
400mg of both DIM and Indole 3 Carbinol
to help reduce the effects of
environmental estrogen on men. There
are prescription drugs available that
block the effects of aromatase (the
human enzyme that stimulates the
conversion of testosterone to
estrogen). The combination of natural
herbal products in this capsule have
been shown to be effective in
controlling the effects of aromatase.
The packaging suggests 1 capsule a day.
Dr. Sears recommends more - up to 400mg
of each ingredient daily.
DESCRIPTION: Ultra Indinol Plus
supplies significant amounts of
indole-3-carbinol(I3C) and
diindolylmethane (DIM) in a proprietary
blend of cruciferous vegetables.
FUNCTIONS: Indole-3-carbinol is a
member of the class of sulfur-containing
chemicals called glucosinolates. It is
found in high amounts in cruciferous
vegetables such as broccoli,
cauliflower, and brussel sprouts.
Indole-3-carbinol acts as an
antioxidant, can stimulate natural
detoxification enzymes and supports
normal hormone metabolism. In the body,
Indole 3-carbinol can be broken down
into diindolylmethane(DIM), another
indole compound that also has similar
health benefits. Cruciferous vegetables,
broccoli and cauliflower, offer
protective sulforophane compounds known
for their ability to induce protective
detoxifying enzymes.
INDICATIONS:
Ultra Indinol Plus may be a useful
dietary supplement for individuals
wishing to supplement their diet with
indole-3-carbinol and diindolylmethane.
Standardized Broccoli, Cauliflower
and Brussel Sprout
SUGGESTED
USE: Adults take 1 capsule daily
with meals or as directed by physician.
SIDE
EFFECTS: No adverse side effects
reported. HOW SUPPLIED Supplied in
bottles of 60 capsules.
STORAGE:
Store in a cool, dry place, away from
direct light. Keep out of reach of
children.
REFERENCES:
Bonnesen C, Eggleston IM, Hayes JD.
Dietary indoles and isothiocyanates that
are generated from cruciferous
vegetables can both stimulate apoptosis
and confer protection against DNA damage
in human colon cell lines. Cancer Res
2001 Aug 15;61(16):6120-30. Chen DZ, Qi
M, Auborn KJ, Carter TH.
Indole-3-carbinol and diindolylmethane
induce apoptosis of human cervical
cancer cells and in murine
HPV16-transgenic preneoplastic cervical
epithelium. J Nutr 2001
Dec;131(12):3294-302. Frydoonfar HR,
McGrath DR, Spigelman AD. The effect of
indole-3-carbinol and sulforaphane on a
prostate cancer cell line. ANZ J Surg
2003 Mar;73(3):154-6. McAlindon TE,
Gulin J, Chen T, Klug T, Lahita R, Nuite
M. Indole-3-carbinol in women with SLE:
effect on estrogen metabolism and
disease activity. Lupus
2001;10(11):779-83. Nho CW, Jeffery E.
The synergistic upregulation of phase II
detoxification enzymes by glucosinolate
breakdown products in cruciferous
vegetables. Toxicol Appl Pharmacol 2001
Jul 15;174(2):146-52.
These
statements have not been evaluated by
the Food and Drug Administration. This
product is not intended to diagnose,
treat, cure, or prevent any disease.
Manufactured
by Douglas Laboratories
600 Boyce Road Pittsburgh, PA 15205
800-245-4440
Open 9:00 am to 5:00 pm
(CT)
Monday through Friday
Closed on major U.S. holidays
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